Article
Dopamine D1 receptor (DRD1) 5' region haplotypes significantly affect transcriptional activity in vitro.
Neuroscience letters - 16 Nov 2015
Yao Jun, Ding Mei, Pang Hao, Xing Jia-Xin, Xuan Jin-Feng, Wang Bao-Jie
Abstract excerpt
The role of dopamine D1 receptor (DRD1) gene promoter polymorphisms in schizophrenia remains controversial. We aimed to characterize the polymorphisms in the promoter region because little is known about the extent of variance in this region and potential roles in gene transcription activity. In a previous case-control study, we amplified and genotyped the polymorphisms of DRD1 gene. According to its haplotype...
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