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Article

Promoter and intronic variants affect the transcriptional regulation of the human dopamine transporter gene.

Genomics - 1 Nov 2003

Greenwood Tiffany A, Kelsoe John R

Abstract excerpt

We have attempted to identify regions involved in the transcriptional regulation of the DAT1 (HUGO approved symbol SLC6A3) gene that may harbor functional variants predisposing to several neuropsychiatric disorders by examining haplotypes of various 5' and intronic regions for their effect on expression in a dopaminergic cell line. A 1.5-fold difference in regulatory activity was observed between haplotypes of...

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PMID: 14559208
DOI: 10.1016/s0888-7543(03)00142-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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