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Article

Association and synergistic interaction between promoter variants of the DRD4 gene in Japanese schizophrenics.

Journal of human genetics - 1 Jan 2007

Nakajima Mizuho, Hattori Eiji, Yamada Kazuo, Iwayama Yoshimi, Toyota Tomoko, Iwata Yasuhide, Tsuchiya Kenji J, Sugihara Genichi, Hashimoto Kenji, Watanabe Hiroyuki, Iyo Masaomi, Hoshika Akinori, Yoshikawa Takeo

Abstract excerpt

Recent association studies suggest that polymorphisms in the promoter and exon 1 upstream region of the dopamine D4 receptor (DRD4) gene play a functional role in the development of common psychiatric illnesses, although there are also conflicting results. In this study, we re-sequenced this region to identify all genomic variants, and tested them for association with schizophrenia. A total of 570 Japanese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17089069
DOI: 10.1007/s10038-006-0084-3
PMCID: PMC1705471

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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