Article
Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene in schizophrenia.
Schizophrenia research - 1 Dec 2003
Xing Qing-he, Wu Sheng-nan, Lin Zhi-guang, Li Hua-fang, Yang Jian-dong, Feng Guo-yin, Wang Ming-tai, Yang Wei-wei, He Lin
Abstract excerpt
Several studies have suggested that the transcriptional activity of the DRD4 gene may exert an important role in susceptibility to schizophrenia. To address this issue, we studied the association of schizophrenia and polymorphisms including -616C>G, -603T>del, -602G>del, 600G>C, -521C>T, -376C>T and a 120 bp tandem duplication polymorphism (120 bp repeat) in 1.2 kb upstream from the initiation codon in the...
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