Article
Analysis of association between dopamine receptor genes' methylation and their expression profile with the risk of schizophrenia.
Psychiatric genetics - 1 Oct 2013
Kordi-Tamandani Dor Mohammad, Sahranavard Roya, Torkamanzehi Adam
Abstract excerpt
OBJECTIVE: Schizophrenia (SCZ) is a type of psychotic disorder that affects ~1% of the population. Dopamine is one of the major neurotransmitters in the brain and its receptors are associated with a number of psychotic disorders, including SCZ. The aims of the present study were to analyze methylation and the expression profile of dopamine receptor DRD1, DRD2, DRD4, and DRD5 genes in patients with SCZ. MATERIALS...
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