Article
Functional analysis of upstream common polymorphisms of the dopamine transporter gene.
Schizophrenia bulletin - 1 Sept 2010
Bamne Mikhil N, Talkowski Michael E, Chowdari Kodavali V, Nimgaonkar Vishwajit L
Abstract excerpt
The human dopamine transporter (DAT, SLC6A3) has been extensively investigated because of its potential involvement in neuropsychiatric disorders. The core elements responsible for its transcription have been identified. A regulatory role for certain genomic variants upstream to the core promoter is known. Recently, other single-nucleotide polymorphisms (SNPs) have been identified in this region and are thought...
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