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Article

The utility of protein structure as a predictor of site-wise dN/dS varies widely among HIV-1 proteins.

Journal of the Royal Society, Interface - 6 Oct 2015

Meyer Austin G, Wilke Claus O

Abstract excerpt

Protein structure acts as a general constraint on the evolution of viral proteins. One widely recognized structural constraint explaining evolutionary variation among sites is the relative solvent accessibility (RSA) of residues in the folded protein. In influenza virus, the distance from functional sites has been found to explain an additional portion of the evolutionary variation in the external antigenic...

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Identifiers

PMID: 26468068
DOI: 10.1098/rsif.2015.0579
PMCID: PMC4614493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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