Extreme Evolutionary Conservation of Functionally Important Regions in H1N1 Influenza Proteome

Abstract excerpt

The H1N1 subtype of influenza A virus has caused two of the four documented pandemics and is responsible for seasonal epidemic outbreaks, presenting a continuous threat to public health. Co-circulating antigenically divergent influenza strains significantly complicates vaccine development and use. Here, by combining evolutionary, structural, functional, and population information about the H1N1 proteome, we seek...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Influenza Virus Research Studies
• Share to RNA and protein synthesis mechanisms
• Share to vaccines and immunoinformatics approaches