Article
The effect of sequence evolution on protein structural divergence.
Molecular biology and evolution - 1 May 2009
Williams Simon G, Lovell Simon C
Abstract excerpt
The complex constraints imposed by protein structure and function result in varied rates of sequence and structural divergence in proteins. Analysis of sequence differences between homologous proteins can advance our understanding of structural divergence and some of the constraints that govern the evolution of these molecules. Here, we assess the relationship between amino acid sequence and structural...
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