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Article

Patterns of amino acid conservation in human and animal immunodeficiency viruses

29 Aug 2016

Abstract excerpt

MOTIVATION: Due to their high genomic variability, RNA viruses and retroviruses present a unique opportunity for detailed study of molecular evolution. Lentiviruses, with HIV being a notable example, are one of the best studied viral groups: hundreds of thousands of sequences are available together with experimentally resolved three-dimensional structures for most viral proteins. In this work, we use these data...

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PMID: 27587690
DOI: 10.1093/bioinformatics/btw441

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