Article
Sex- and Obesity-specific Association of Aromatase (CYP19A1) Gene Variant with Apolipoprotein B and Hypertension.
Archives of medical research - 1 Oct 2015
Coban Neslihan, Onat Altan, Guclu-Geyik Filiz, Can Gunay, Erginel-Unaltuna Nihan
Abstract excerpt
BACKGROUND AND AIMS: Gender differences in cardiovascular disease risk have been attributed to sex hormones. The CYP19A1 protein (aromatase) plays a critical role in estrogen biosynthesis and thus affects body fat distribution and regulation. We examined the relationship between polymorphism of the CYP19A1 gene and lipoproteins, body mass index (BMI), insulin levels and HOMA index. METHODS: Randomly selected 2250...
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