Article
Association between CYP19A1 polymorphisms and sex hormones in postmenopausal Japanese women.
Journal of human genetics - 1 Feb 2009
Kidokoro Kumiko, Ino Kazuhiko, Hirose Kaoru, Kajiyama Hiroaki, Hosono Satoyo, Suzuki Takeshi, Kawase Takakazu, Hiraki Akio, Hamajima Nobuyuki, Tanaka Hideo, Tajima Kazuo, Kikkawa Fumitaka, Matsuo Keitaro
Abstract excerpt
In postmenopausal women, extraovarian sex hormone production plays an important role in hormone-related diseases, such as breast and endometrial cancers. Aromatase, an enzyme encoded by CYP19A1, is a key enzyme involved in estrogen biosynthesis. The impact of CYP19A1 polymorphisms on serum sex hormone levels in the Japanese population has never been investigated. This study enrolled 100 postmenopausal Japanese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
