Article
Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women.
Pharmacogenetics and genomics - 1 Aug 2008
Cai Hui, Shu Xiao Ou, Egan Kathleen M, Cai Qiuyin, Long Ji-Rong, Gao Yu-Tang, Zheng Wei
Abstract excerpt
OBJECTIVE: Circulating estrogen levels have been related to the risk of several female cancers. Blood levels of estrogen are controlled by estrogen synthesis enzymes. Genetic variation of estrogen genes thus may influence circulating estrogen levels. We investigated the associations of genetic polymorphisms in CYP19A1, a critical gene involved in estrogen synthesis, with plasma levels of sex hormones among...
Topics
- Adult
- Aromatase
- Asian People
- Body Mass Index
- China
- Confidence Intervals
- Estradiol
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- Gonadal Steroid Hormones
