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Article

Aromatase gene polymorphisms are associated with survival among patients with cardiovascular disease in a sex-specific manner.

PloS one - 10 Dec 2010

Beitelshees Amber L, Johnson Julie A, Hames Megan L, Gong Yan, Cooper-Dehoff Rhonda M, Wu Jun, Cresci Sharon, Ma Cynthia X, Pepine Carl J, Province Michael A, Spertus John A, McLeod Howard L

Abstract excerpt

INTRODUCTION: CYP19A1 encodes aromatase, the enzyme responsible for the conversion of androgens to estrogens, and may play a role in variation in outcomes among men and women with cardiovascular disease. We sought to examine genetic variation in CYP19A1 for its potential role in sex differences in cardiovascular disease outcomes. METHODS: Caucasian individuals from two independent populations were assessed: 1) a...

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PMID: 21170323
DOI: 10.1371/journal.pone.0015180
PMCID: PMC3000815

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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