Article
Association study of aromatase gene (CYP19A1) in essential hypertension.
International journal of medical sciences - 7 Feb 2008
Shimodaira Masanori, Nakayama Tomohiro, Sato Naoyuki, Saito Kosuke, Morita Akihiko, Sato Ichiro, Takahashi Teruyuki, Soma Masayoshi, Izumi Yoichi
Abstract excerpt
BACKGROUND: As aromatase-deficient mice, which are deficient in estrogens, reportedly have reduced blood pressure, the aromatase gene (CYP19A1) is thought to be a susceptibility gene for essential hypertension (EH). The aim of the present study was to investigate the relationship between CYP19A1 and EH by examining single nucleotide polymorphisms (SNPs). METHODS: Five SNPs in the human CYP19A1 gene (rs1870049,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.