Article
A Novel Polymorphism of the CYP19 Gene is Associated with Essential Hypertension in China.
Clinical laboratory - 1 Jan 2016
Fu Yan-zhen, Wang Bei, Ma Tong-yi, Huang Ding, Liu Fen, Dong Lan-chun, Wang Ting, Meng Jie-ya
Abstract excerpt
BACKGROUND: Aromatase which is encoded by the CYP19 gene is a key enzyme in the conversion of androgen to estrogen and plays an important role in the balance of the gender hormone levels. The gender hormone has a causal role in the development of cardiovascular disease. The goal of this study was to investigate the interaction between the SNPs in CYP19 gene and essential hypertension. METHODS: The case-control...
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