Article
Influence of UGT2B7, CYP3A4, and OPRM1 Gene Polymorphisms on Transdermal Buprenorphine Pain Control in Patients with Critical Lower Limb Ischemia Awaiting Revascularization.
Pain practice : the official journal of World Institute of Pain - 1 Sept 2016
Blanco Francisco, Muriel Clemente, Labrador Jorge, Gonzalez-Porras Jose R, Gonzalez-Sarmiento Rogelio, Lozano Francisco S
Abstract excerpt
BACKGROUND: Pain control in critical limb ischemia (CLI) varies considerably between individuals. OBJECTIVE: To evaluate pharmacogenetically the response to transdermal buprenorphine (BUP-TTS) in patients with CLI who are awaiting revascularization. METHODS: One hundred and seven patients with CLI were treated with BUP-TTS. The following were analyzed: (1) pain perception (visual analog scale (VAS) before and 4...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.