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Article

Influence of uridine diphosphate-glucuronyltransferase 2B7 (UGT2B7) variants on postoperative buprenorphine analgesia.

Pain practice : the official journal of World Institute of Pain - 1 Jan 2015

Sastre José A, Varela Gonzalo, López Mónica, Muriel Clemente, González-Sarmiento Rogelio

Abstract excerpt

BACKGROUND: Genetic factors are known to influence individual differences in pain and sensitivity to analgesics. Different genetic polymorphisms in opioid-metabolizing enzymes that can affect the analgesic response to opioids have been proposed. This study investigates a possible difference in the response to postoperative buprenorphine analgesia related to the presence of different isoforms (cytosine or thymine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24256307
DOI: 10.1111/papr.12152

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