Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Postamputation pain and sensory changes in treatment-naive patients: characteristics and responses to treatment with tramadol, amitriptyline, and placebo.

Anesthesiology - 1 Sept 2005

Wilder-Smith Clive H, Hill Lauren T, Laurent Sophie

Abstract excerpt

BACKGROUND: Pain after amputation is common but difficult to treat, and few controlled treatment studies exist. METHODS: In the current study, 94 treatment-naive posttraumatic limb amputees with phantom pain (intensity: mean visual analog scale score [0-100], 40 [95% confidence interval, 38-41]) were randomly assigned to receive individually titrated doses of tramadol, placebo (double-blind comparison), or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Pain Measurement

Share to Pain Threshold

Share to Phenotype

Source

Identifiers

PMID: 16129989
DOI: 10.1097/00000542-200509000-00027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Postamputation pain and sensory changes in treatment-naive patients: characteristics and responses to treatment with tramadol, amitriptyline, and placebo.PMID 16129989Read ↗

Surgical Treatments for Post-amputation Pain: Study Protocol for an International, Double-blind, Randomised Controlled TrialSemantic proximity Read ↗

Nerve trauma-caused downregulation of opioid receptors in primary afferent neurons: Molecular mechanisms and potential managementsSemantic proximity Read ↗

Influence of UGT2B7, CYP3A4, and OPRM1 Gene Polymorphisms on Transdermal Buprenorphine Pain Control in Patients with Critical Lower Limb Ischemia Awaiting Revascularization.Semantic proximity Read ↗

Efficacy of radiofrequency ablation versus ethanol ablation for Morton's neuroma: a clinical trial using patient recorded outcome measuresSemantic proximity Read ↗

30-day and lasting impacts on utilizing a novel orthotic insole for tactile stimulation in diabetic peripheral neuropathy: a double-blind, randomized, sham-controlled trialSemantic proximity Read ↗

Analgesic Effect of a 5% Lidocaine Patch in Patients With Opioid Treatment-Resistant Neuropathic Cancer PainSemantic proximity Read ↗

Prolonged critical avalanche burial for nearly 23 hours with severe hypothermia and severe frostbite with good recovery: A case reportSemantic proximity Read ↗

Comparative Clinical Effectiveness, Safety, and Cost-Effectiveness of Intravenous Tramadol versus Metamizole for Post-Procedural Pain ManagementSemantic proximity Read ↗

Management of Central Post-Stroke Pain: Systematic Review and Meta-AnalysisSemantic proximity Read ↗

Decreased Analgesic Effect of Tramadol in Japanese Patients with CYP2D6 Intermediate Metabolizers after Orthopedic Surgery.Semantic proximity Read ↗

Influence of surface peripheral electrical stimulation on nerve regeneration after digital nerve neurorrhaphy: study protocol for a randomized clinical trialSemantic proximity Read ↗

Amputee, clinician, and regulator perspectives on current and prospective upper extremity prosthetic technologiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.