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Article

A logistic equation to determine the validity of tramadol from related gene polymorphisms and psychological factors.

Pharmacogenomics - 1 Mar 2014

Zhao Qin, Sun Jianguo, Tao Yifu, Wang Shukui, Jiang Chunzhi, Zhu Yubing, Yu Feng, Zhu Junrong

Abstract excerpt

AIM: This study was performed to develop an algorithm using polymorphisms of CYP2D6, p-gp, OPRM1, COMT and psychological variables to predict tramadol response in Chinese patients recovering from upper limb fracture internal fixation surgery. METHODS: A total of 250 Han Chinese patients recovering from fracture in the upper limb were enrolled. CYP2D6*10, p-gp G2677T, p-gp C3435T, OPRM1 A118G and COMT Val158Met...

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Topics

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Share to Analgesics, Opioid
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Cytochrome P-450 CYP2D6

Share to Fractures, Bone

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Share to Receptors, Opioid, mu

Source

Identifiers

PMID: 24624916
DOI: 10.2217/pgs.14.22

Genes

COMT
OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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