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Article

Functional analysis of CedA based on its structure: residues important in binding of DNA and RNA polymerase and in the cell division regulation.

Journal of biochemistry - 1 Feb 2016

Abe Yoshito, Fujisaki Naoki, Miyoshi Takanori, Watanabe Noriko, Katayama Tsutomu, Ueda Tadashi

Abstract excerpt

DnaAcos, a mutant of the initiator DnaA, causes overinitiation of chromosome replication in Escherichia coli, resulting in inhibition of cell division. CedA was found to be a multi-copy suppressor which represses the dnaAcos inhibition of cell division. However, functional mechanism of CedA remains elusive except for previously indicated possibilities in binding to DNA and RNA polymerase. In this study, we...

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Identifiers

PMID: 26400504
DOI: 10.1093/jb/mvv096
PMCID: PMC4892778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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