Article
Modulation of clonal progression in B16F1 melanoma cells.
Clinical & experimental metastasis - 1 Jan 2000
Harris J F, Chambers A F, Tam A S
Abstract excerpt
We have examined the effects of the microenvironment on the frequency and generation of metastatic variant cells in both parental B16F1 melanoma cells and nascent clones. The metastatic abilities of cultured B16F1 cells were tested after a period of growth in the presence or absence of a second cell population separated from each other by a transwell membrane (0.45 micron pore size). The first population is...
Topics
- Animals
- Cell Survival
- Melanoma, Experimental
- Mice
- Neoplasm Metastasis
- Phenotype
- Tumor Cells, Cultured
