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Article

Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1-MRP1) in the Polish population.

BMC genetics - 23 Sept 2015

Słomka Marcin, Sobalska-Kwapis Marta, Korycka-Machała Małgorzata, Bartosz Grzegorz, Dziadek Jarosław, Strapagiel Dominik

Abstract excerpt

BACKGROUND: Multidrug resistance-associated protein 1 (MRP1), encoded by the ABCC1 gene, is an ATP-binding cassette transporter mediating efflux of organic anions and xenobiotics; its overexpression leads to multidrug resistance. In this study, 30 exons (from 31 in total) of the ABCC1 gene as well as and their flanking intron sequences were screened for genetic variation, using the High Resolution Melting (HRM)...

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Identifiers

PMID: 26395522
DOI: 10.1186/s12863-015-0271-3
PMCID: PMC4579605

Genes

ABCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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