Article
Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population.
Pharmacogenetics and genomics - 1 Mar 2009
Yin Ji-Ye, Huang Qiong, Yang Youyun, Zhang Jian-Ting, Zhong Mei-Zuo, Zhou Hong-Hao, Liu Zhao-Qian
Abstract excerpt
OBJECTIVE: To explore the distribution frequencies of four common single nucleotide polymorphisms (SNPs) of MRP1/ABCC1 in a mainland Chinese population and investigate whether these SNPs affect the expression and function of the MRP1/ABCC1. METHODS: The genotype of 208 healthy volunteers was determined using PCR-restriction fragment length polymorphism. The four candidated SNPs were recreated by site-directed...
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