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Article

Genetic variations and haplotypes of ABCC2 encoding MRP2 in a Japanese population.

Drug metabolism and pharmacokinetics - 1 Jan 2008

Sai Kimie, Saito Yoshiro, Itoda Masaya, Fukushima-Uesaka Hiromi, Nishimaki-Mogami Tomoko, Ozawa Shogo, Maekawa Keiko, Kurose Kouichi, Kaniwa Nahoko, Kawamoto Manabu, Kamatani Naoyuki, Shirao Kuniaki, Hamaguchi Tetsuya, Yamamoto Noboru, Kunitoh Hideo, Ohe Yuichiro, Yamada Yasuhide, Tamura Tomohide, Yoshida Teruhiko, Minami Hironobu, Matsumura Yasuhiro, Ohtsu Atsushi, Saijo Nagahiro, Sawada Jun-ichi

Abstract excerpt

The multidrug resistance-associated protein 2 (MRP2) encoded by the ABCC2 gene is expressed in the liver, intestine and kidneys and preferentially exports organic anions or conjugates with glucuronide or glutathione. In this study, all 32 exons and the 5'-flanking region of ABCC2 in 236 Japanese...

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Identifiers

PMID: 18445995
DOI: 10.2133/dmpk.23.139

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18445995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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