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Article

Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Oct 2011

Yin Jiye, Zhang Jianting

Abstract excerpt

Multidrug resistance-associated protein 1(MRP1/ABCC1) is the first identified member of ABCC subfamily which belongs to ATP-binding cassette (ABC) transporter superfamily. It is ubiquitously expressed in almost all human tissues and transports a wide spectrum of substrates including drugs, heavy metal anions, toxicants, and conjugates of glutathione, glucuronide and sulfate. With the advance of sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22086004
DOI: 10.3969/j.issn.1672-7347.2011.10.002
PMCID: PMC4297474

Genes

ABCC1

Provenance

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Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application.PMID 22086004Read ↗

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