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Article

Genetic variations and haplotype structures of the ABC transporter gene ABCC1 in a Japanese population.

Drug metabolism and pharmacokinetics - 25 Feb 2007

Fukushima-Uesaka Hiromi, Saito Yoshiro, Tohkin Masahiro, Maekawa Keiko, Hasegawa Ryuichi, Kawamoto Manabu, Kamatani Naoyuki, Suzuki Kazuko, Yanagawa Tatsuo, Kajio Hiroshi, Kuzuya Nobuaki, Yasuda Kazuki, Sawada Jun-ichi

Abstract excerpt

Multidrug resistance-related protein 1 (MRP1), an ATP-binding cassette transporter encoded by the ABCC1 gene, is expressed in many tissues, and functions as an efflux transporter for glutathione-, glucuronate- and sulfate-conjugates as well as unconjugated substrates. In this study, the 31 exons and their flanking introns of ABCC1 were comprehensively screened for genetic variations in 153 Japanese subjects to...

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Identifiers

PMID: 17329911
DOI: 10.2133/dmpk.22.48

Genes

ABCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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