TERT promoter mutations in soft tissue sarcomas.

doi:10.5301/jbm.5000168

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Article

TERT promoter mutations in soft tissue sarcomas.

The International journal of biological markers - 28 Feb 2016

Campanella Nathália C, Penna Valter, Abrahão-Machado Lucas Faria, Cruvinel-Carloni Adriana, Ribeiro Guilherme, Soares Paula, Scapulatempo-Neto Cristovam, Reis Rui M

Abstract excerpt

INTRODUCTION: Oncogenic hotspot mutations in the promoter region of the TERT gene have been identified in several cancer types as being associated with a worse outcome. Additionally, a polymorphism (rs2853669) in the TERT promoter region was reported to modify the survival of TERT-mutated patients. Our aim is to determine the frequency of c.-124 C>T and c.-146 C>T TERT mutations and to genotype the...

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Identifiers

PMID: 26391479
DOI: 10.5301/jbm.5000168

Genes

TERT
STS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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