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Article

Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas.

International journal of molecular sciences - 18 Feb 2018

Ferreira Monica S Ventura, Crysandt Martina, Braunschweig Till, Jost Edgar, Voss Barbara, Bouillon Anne-Sophie, Knuechel Ruth, Brümmendorf Tim H, Beier Fabian

Abstract excerpt

The occurrence of TERT promoter mutations has been well described in soft tissue sarcomas (STS). However, the biological role of these mutations as well as their impact on telomere length in STS is still unclear. We analyzed 116 patient samples diagnosed with 22 distinct histological subtypes of bone and STS for the occurrence of TERT promoter mutations by Sanger sequencing. We observed TERT promoter mutations at...

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Share to Bone Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Neoplasm Grading

Share to Promoter Regions, Genetic

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Source

Open in PubMed Open full text

Identifiers

PMID: 29463038
DOI: 10.3390/ijms19020608
PMCID: PMC5855830

Genes

TERT
STS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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