Article
TERT promoter mutations in solitary fibrous tumour.
Histopathology - 1 Nov 2018
Demicco Elizabeth G, Wani Khalida, Ingram Davis, Wagner Michael, Maki Robert G, Rizzo Anthony, Meeker Alan, Lazar Alexander J, Wang Wei-Lien
Abstract excerpt
AIMS: TERT promoter mutations have been reported in 22% of solitary fibrous tumours (SFT) and have been associated with poor outcomes. We performed testing for TERT hot-spot mutations in a large series of SFT in order to confirm this finding and explore clinicopathological correlates of mutation status. METHODS AND RESULTS: PCR for TERT hot-spot mutations C250T and C228T was performed on DNA extracted from 216...
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