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Promoter region mutations of the telomerase reverse transcriptase (TERT) gene in head and neck squamous cell carcinoma.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Jul 2020

Yilmaz Ismail, Erkul Bulent Evren, Ozturk Sari Sule, Issin Gizem, Tural Ersin, Terzi Kaya Terzi Neslihan, Karatay Huseyin, Celik Mehmet, Ulusan Murat, Bilgic Bilge

Abstract excerpt

OBJECTIVE: The aim of the present study was to assess the prevalence of TERT promoter region mutations in tumor samples of patients with squamous cell carcinoma at different sites of the head and neck region and correlate it with patients' clinicopathologic data. STUDY DESIGN: Mutations in promoter region of the TERT gene were analyzed with polymerase chain reaction-based direct sequencing method using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32404253
DOI: 10.1016/j.oooo.2020.02.015

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