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CD39 expression on Treg and Th17 cells is associated with metabolic factors in patients with type 2 diabetes.

Human immunology - 1 Sept 2015

Cortez-Espinosa Nancy, Cortés-Garcia Juan Diego, Martínez-Leija Ernesto, Rodríguez-Rivera Jose Guillermo, Barajas-López Carlos, González-Amaro Roberto, Portales-Pérez Diana Patricia

Abstract excerpt

Th17 cells are involved in the pathogenesis of multiple inflammatory diseases such as type two diabetes (T2D). CD39(+) Treg cells have been implicated as responsible for suppressing Th17 cells. The aim of this study was to evaluate the number and function of CD4(+)CD25(high)CD39(+) Treg and Th17 cells in peripheral blood mononuclear cells (PBMC) from T2D patients and healthy control subjects. The Th17 cells were...

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PMID: 26386144
DOI: 10.1016/j.humimm.2015.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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