Article
Use of Tregs as a cell-based therapy via CD39 for benign prostate hyperplasia with inflammation.
Journal of cellular and molecular medicine - 1 May 2020
Jin Xi, Lin Tianhai, Yang Guang, Cai Huawei, Tang Bo, Liao Xinyang, Li Huifang, Chen Xiaoting, Gong Lina, Xu Hang, Sun Yi, Tan Ping, Yin Jianqiong, Ma Hongwen, Ai Jianzhong, Wang Kunjie, Wei Qiang, Yang Lu, Li Hong
Abstract excerpt
Benign prostatic hyperplasia (BPH) occurs most commonly among older men, often accompanied by chronic tissue inflammation. Although its aetiology remains unclear, autoimmune dysregulation may contribute to BPH. Regulatory T cells (Tregs) prevent autoimmune responses and maintain immune homeostasis. In this study, we aimed to investigate Tregs frequency, phenotype, and function in BPH patients and to evaluate...
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