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Article

Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets.

Journal of immunological methods - 30 Jun 2011

Schuler Patrick J, Harasymczuk Malgorzata, Schilling Bastian, Lang Stephan, Whiteside Theresa L

Abstract excerpt

OBJECTIVE: The ectonucleotidase CD39 is an enzyme involved in adenosine production. Its surface expression on human regulatory T cells (Treg) allows for their flow-cytometry-based isolation from peripheral blood. To further develop and improve this method on a scale supporting translational studies, we introduced capture of CD39(+) Treg on magnetic immunobeads. METHODS: Peripheral blood mononuclear cells (PBMC)...

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Source

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Identifiers

PMID: 21513715
DOI: 10.1016/j.jim.2011.04.004
PMCID: PMC3120012

Genes

FOXP3
CCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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