Article
Elevated peripheral frequencies of Th22 cells: a novel potent participant in obesity and type 2 diabetes.
PloS one - 1 Jan 2014
Zhao Ruxing, Tang Dongqi, Yi Shounan, Li Wenjuan, Wu Chuanlong, Lu Yiran, Hou Xinguo, Song Jun, Lin Peng, Chen Li, Sun Lei
Abstract excerpt
OBJECTIVE: Chronic low-grade inflammation has long been recognized as the central link between obesity and type 2 diabetes (T2D). The novel subset of T helper (Th) cells, Th22, plays an emerging role in chronic inflammation. We investigated the potential association between Th22 and the pathogenesis of obesity and T2D. METHODS: Ninety T2D inpatients (T2D group), 30 healthy participants with BMI ranged from 19 to...
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