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Article

Increased CD4(+) CD69(+) CD25(-) T cells in patients with hepatocellular carcinoma are associated with tumor progression.

Journal of gastroenterology and hepatology - 1 Oct 2011

Zhu Jiankang, Feng Alei, Sun Jintang, Jiang Zhenzhong, Zhang Guangyong, Wang Kexin, Hu Sanyuan, Qu Xun

Abstract excerpt

BACKGROUND AND AIM: A new subset of Treg cells, CD4(+) CD69(+) CD25(-) T cells, has been identified in mice. Herein, we aimed to identify this subset of T cells and to evaluate its function in patients with hepatocellular carcinoma (HCC). METHODS: We detected CD4(+) CD69(+) CD25(-) T cells and it...

Read the complete abstract on PubMed

Topics

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Share to Antigens, Differentiation, T-Lymphocyte
Share to CD4 Lymphocyte Count
Share to Interleukin-2 Receptor alpha Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins, C-Type

Share to Lymphocytes, Tumor-Infiltrating

Share to T-Lymphocytes, Regulatory

Share to Transforming Growth Factor beta1

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Source

Identifiers

PMID: 21557772
DOI: 10.1111/j.1440-1746.2011.06765.x

Genes

CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21557772-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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