Article
Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis.
Proceedings of the National Academy of Sciences of the United States of America - 2 May 2006
Recht J, Tsubota T, Tanny J C, Diaz R L, Berger J M, Zhang X, Garcia B A, Shabanowitz J, Burlingame A L, Hunt D F, Kaufman P D, Allis C D
Abstract excerpt
Histone acetylation affects many nuclear processes including transcription, chromatin assembly, and DNA damage repair. Acetylation of histone H3 lysine 56 (H3 K56ac) in budding yeast occurs during mitotic S phase and persists during DNA damage repair. Here, we show that H3 K56ac is also present during premeiotic S phase and is conserved in fission yeast. Furthermore, the H3 K56ac modification is not observed in...
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