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Article

Prevalence and spectrum of p53 mutations associated with smoking in breast cancer.

Cancer research - 1 Apr 2002

Conway Kathleen, Edmiston Sharon N, Cui Lisa, Drouin S Scott, Pang Jingzhong, He Mei, Tse Chiu-Kit, Geradts Joseph, Dressler Lynn, Liu Edison T, Millikan Robert, Newman Beth

Abstract excerpt

To explore the role of smoking in breast cancer, we undertook a population-based study to evaluate the prevalence and spectrum of p53 mutations in the breast tumors of smokers and nonsmokers. We evaluated 456 archival invasive breast tumors for mutations in exons 4-8 of the p53 gene, using single-strand conformational polymorphism analysis and manual sequencing. Statistical analyses were performed to determine...

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Identifiers

PMID: 11929815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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