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Article

Clinical implications of germline mutations in breast cancer: TP53.

Breast cancer research and treatment - 1 Jan 2018

Schon Katherine, Tischkowitz Marc

Abstract excerpt

PURPOSE: This review describes the prevalence of germline TP53 mutations, the risk of breast cancer and other cancers in mutation carriers and management implications for women with breast cancer and unaffected women. METHODS: Literature review of English language papers available through PubMed. RESULTS: Women who carry germline mutations in the TP53 gene have a very high risk of breast cancer of up to 85% by...

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Identifiers

PMID: 29039119
DOI: 10.1007/s10549-017-4531-y
PMCID: PMC5790840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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