Article
Serotonin transporter gene polymorphism modulates inflammatory cytokine responses during acute stress.
Scientific reports - 9 Sept 2015
Yamakawa Kaori, Matsunaga Masahiro, Isowa Tokiko, Ohira Hideki
Abstract excerpt
Cytokines are important mediators of various stress-related modulations of immune function. A major genetic factor determining inter-individual differences in stress reactivity is polymorphisms of the serotonin (5-hydroxytryptamine, 5HT) transporter (5HTT) gene. A short (S) variant, compared with a long (L) variant, of the promoter region of the 5HTT gene-linked polymorphic region (5HTTLPR) has been related to...
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