Article
Healthy young women with serotonin transporter SS polymorphism show a pro-inflammatory bias under resting and stress conditions.
Brain, behavior, and immunity - 1 Mar 2010
Fredericks Carolyn A, Drabant Emily M, Edge Michael D, Tillie Jean M, Hallmayer Joachim, Ramel Wiveka, Kuo Janice R, Mackey Sean, Gross James J, Dhabhar Firdaus S
Abstract excerpt
The study of functionally relevant biological effects of serotonin transporter gene promoter region (5-HTTLPR) polymorphisms is especially important given the current controversy about the clinical relevance of these polymorphisms. Here we report an intrinsic immunobiological difference between individuals carrying two short (SS) versus long (LL) 5-HTTLPR alleles, that is observed in healthy subjects reporting...
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