Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association of the 5-HTTLPR polymorphism and the response to different stressors in healthy males.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2021

Kuhn Leandra, Noack Hannes, Skoluda Nadine, Wagels Lisa, Röhr Ann-Kristin, Schulte Christina, Eisenkolb Sana, Nieratschker Vanessa, Derntl Birgit, Habel Ute

Abstract excerpt

The experience of stress is related to individual wellbeing and vulnerability to psychopathology. Therefore, understanding the determinants of individual differences in stress reactivity is of great concern from a clinical perspective. The functional promotor polymorphism of the serotonin transporter gene (5-HTTLPR/rs25531) is such a factor, which has been linked to the acute stress response as well as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrocortisone

Share to Polymorphism, Genetic

Share to Serotonin Plasma Membrane Transport Proteins

Share to Stress, Psychological

Source

Open in PubMed Open full text

Identifiers

PMID: 34374855
DOI: 10.1007/s00702-021-02390-4
PMCID: PMC8423678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association of the 5-HTTLPR polymorphism and the response to different stressors in healthy males.PMID 34374855Read ↗

Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burdenSemantic proximity Read ↗

Influence of psychosocial stress on activation in human brain regions: moderation by the 5-HTTLPR genetic locus.Semantic proximity Read ↗

Differential effects of 5-HTTLPR genotypes on inhibition of negative emotional information following acute stress exposure and tryptophan challenge.Semantic proximity Read ↗

The serotonin transporter promoter polymorphism is associated with cortisol response to psychosocial stress.Semantic proximity Read ↗

The HTR1A and HTR1B receptor genes influence stress-related information processing.Semantic proximity Read ↗

Stressing over anxiety: A novel interaction of 5-HTTPLR genotype and anxiety-related phenotypes in older adults.Semantic proximity Read ↗

Gene-environment interactions predict cortisol responses after acute stress: implications for the etiology of depression.Semantic proximity Read ↗

Differential effects of tri-allelic 5-HTTLPR polymorphisms in healthy subjects on mood and stress performance after tryptophan challenge.Semantic proximity Read ↗

Interaction effect of D4 dopamine receptor gene and serotonin transporter promoter polymorphism on the cortisol stress response.Semantic proximity Read ↗

Differential effects of 5-HTTLPR genotypes on mood, memory, and attention bias following acute tryptophan depletion and stress exposure.Semantic proximity Read ↗

Polymorphism of the serotonin transporter gene modulates brain and physiological responses to acute stress in Japanese men.Semantic proximity Read ↗

An integrative review of methylation at the serotonin transporter gene and its dialogue with environmental risk factors, psychopathology and 5-HTTLPR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.