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Article

Polymorphism of the serotonin transporter gene modulates brain and physiological responses to acute stress in Japanese men.

Stress (Amsterdam, Netherlands) - 1 Nov 2009

Ohira Hideki, Matsunaga Masahiro, Isowa Tokiko, Nomura Michio, Ichikawa Naho, Kimura Kenta, Kanayama Noriaki, Murakami Hiroki, Osumi Takahiro, Konagaya Toshihiro, Nogimori Tsuyoshi, Fukuyama Seisuke, Shinoda Jun, Yamada Jitsuhiro

Abstract excerpt

A short (S) variant, compared to a long (L) variant, of the promoter region of the serotonin transporter gene-linked polymorphic region (5HTTLPR) has been related to emotional hyper-reactivity. We tested whether the 5HTTLPR could modulate acute stress responses in the brain and, the cardiovascular and neuroendocrine systems. Ten Japanese male participants carrying double copies of the S alleles and 10 Japanese...

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PMID: 19658029
DOI: 10.3109/10253890902787826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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