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Article

Shear stress-induced atherosclerotic plaque composition in ApoE(-/-) mice is modulated by connexin37.

Atherosclerosis - 1 Nov 2015

Pfenniger A, Meens M J, Pedrigi R M, Foglia B, Sutter E, Pelli G, Rochemont V, Petrova T V, Krams R, Kwak B R

Abstract excerpt

OBJECTIVE: Shear stress patterns influence atherogenesis and plaque stability; low laminar shear stress (LLSS) promotes unstable plaques whereas oscillatory shear stress (OSS) induces more stable plaques. Endothelial connexin37 (Cx37) expression is also regulated by shear stress, which may contribute to localization of atherosclerotic disease. Moreover, Cx37 reduces initiation of atherosclerosis by inhibiting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26342936
DOI: 10.1016/j.atherosclerosis.2015.08.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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