Article
Serial F-18-FDG PET/CT distinguishes inflamed from stable plaque phenotypes in shear-stress induced murine atherosclerosis.
Atherosclerosis - 1 Jun 2014
Wenning Christian, Kloth Christopher, Kuhlmann Michael T, Jacobs Andreas H, Schober Otmar, Hermann Sven, Schäfers Michael A
Abstract excerpt
BACKGROUND: Detection of inflamed atherosclerotic plaques is of crucial importance. The carotid artery cuff-model in ApoE(-/-) mice results in shear-stress induced atherosclerosis with inflamed plaques upstream (US) and 'stable' plaques downstream (DS) of the cuff. We evaluated the potential of F-18-FDG PET/CT to differentiate these plaque phenotypes. METHODS: A predefined cuff was implanted round the left (n =...
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