Article
Hemodynamic shear stress and its role in atherosclerosis.
JAMA - 1 Dec 1999
Malek A M, Alper S L, Izumo S
Abstract excerpt
Atherosclerosis, the leading cause of death in the developed world and nearly the leading cause in the developing world, is associated with systemic risk factors including hypertension, smoking, hyperlipidemia, and diabetes mellitus, among others. Nonetheless, atherosclerosis remains a geometrically focal disease, preferentially affecting the outer edges of vessel bifurcations. In these predisposed areas,...
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