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Article

Fibromodulin deficiency reduces low-density lipoprotein accumulation in atherosclerotic plaques in apolipoprotein E-null mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2013

Shami Annelie, Gustafsson Renata, Kalamajski Sebastian, Krams Rob, Segers Dolf, Rauch Uwe, Roos Gunnel, Nilsson Jan, Oldberg Åke, Hultgårdh-Nilsson Anna

Abstract excerpt

OBJECTIVE: The aim of this study was to analyze how an altered collagen structure affects development of atherosclerotic plaques. METHODS AND RESULTS: Fibromodulin-null mice develop an abnormal collagen fibril structure. In apolipoprotein E (ApoE)-null and ApoE/fibromodulin-null mice, a shear stress-modifying carotid artery cast induced formation of atherosclerotic plaques of different phenotypes; inflammatory in...

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Identifiers

PMID: 23202368
DOI: 10.1161/ATVBAHA.112.300723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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