Article
Molecular Basis of the Membrane Interaction of the β2e Subunit of Voltage-Gated Ca(2+) Channels.
Biophysical journal - 1 Sept 2015
Kim Dong-Il, Kang Mooseok, Kim Sangyeol, Lee Juhwan, Park Yongsoo, Chang Iksoo, Suh Byung-Chang
Abstract excerpt
The auxiliary β subunit plays an important role in the regulation of voltage-gated calcium (CaV) channels. Recently, it was revealed that β2e associates with the plasma membrane through an electrostatic interaction between N-terminal basic residues and anionic phospholipids. However, a molecular-level understanding of β-subunit membrane recruitment in structural detail has remained elusive. In this study, using a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
