Article
Regulation of neuronal SNARE assembly by the membrane.
Nature structural biology - 1 Jun 2003
Kweon Dae-Hyuk, Kim Chang Sup, Shin Yeon-Kyun
Abstract excerpt
In the neuron, SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) assembly acts centrally in driving membrane fusion, a required process for neurotransmitter release. In the cytoplasm, vesicular SNARE VAMP-2 (vesicle-associated membrane protein-2) engages with two plasma membrane SNAREs, syntaxin 1A and SNAP-25 (synaptosome-associated protein of 25 kDa), to form the core complex that...
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