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Article

The N terminus of a schistosome beta subunit regulates inactivation and current density of a Cav2 channel.

The Journal of biological chemistry - 12 Nov 2010

Salvador-Recatalà Vicenta, Greenberg Robert M

Abstract excerpt

The β subunit of high voltage-activated Ca(2+) (Ca(v)) channels targets the pore-forming α(1) subunit to the plasma membrane and tunes the biophysical phenotype of the Ca(v) channel complex. We used a combination of molecular biology and whole-cell patch clamp to investigate the functional role of a long N-terminal polyacidic motif (NPAM) in a Ca(v)β subunit of the human parasite Schistosoma mansoni (β(Sm)), a...

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Identifiers

PMID: 20826800
DOI: 10.1074/jbc.M110.144725
PMCID: PMC2975211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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